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Ayanda Nqeketo grew up in Ngqeleni, near Umthatha in the Eastern Cape, and has an MA degree in Medical Anthropology from the University of the Western Cape. He has extensive experience in public health, community outreach and the coordination of field studies, particularly in the areas of HIV/AIDS and traditional male initiation (TMI). He has worked with government departments, agencies and organisations to
offer technical support and advice on community issues around project implementation in specific focus areas.

Ayanda is the founder and Director of Ikamva Lesizwe Institute (Ikamva), which collaborates with stakeholders who seek to implement programmes in local communities. He has co-published in academic journals, and has penned newspaper columns on HIV/AIDS and male circumcision.

In 2018, Ayanda was appointed to the World Health Organisation as a member of the Guideline Development Group (GDG) on safe male circumcision for HIV prevention. He lives in Tshwane with his wife and children.